En un modelo murino se encontraron algunos cambios metabólicos en macrófagos inducidos por exposición a critales de sílice: afectación de la respiración mitocondrial y supresión de la liberación de IFN-ß. Los resultados son presentados en Marrocco A, Frawley K, Pearce LL, Peterson J, O’Brien JP, Mullett SJ, et al. Metabolic Adaptation of Macrophages as Mechanism of Defense against Crystalline Silica. J Immunol September 15, 2021;207(6):1627-1640.
– Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity
– Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms
– A novel strategy for SARS-CoV-2 mass screening with quantitative antigen testing of saliva: a diagnostic accuracy study
– Lessons Learned from Cutting-Edge Immunoinformatics on Next-Generation COVID-19 Vaccine Research
– Immunoinformatics approach for multi-epitope vaccine design against structural proteins and ORF1a polyprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
– Immunoinformatics study to search epitopes of spike glycoprotein from SARS-CoV-2 as potential vaccine
En la sección: COVID-19, Infectología, Inmunidad innata, Vacunología. Publicado en: .
– Role of Pegylated Interferon in Patients with Chronic Liver Diseases in the Context of SARS-CoV-2 Infection
– Interferon-lambda 3 and 4 Polymorphisms Increase Sustained Virological Responses and Regulate Innate Immunity in Antiviral Therapy With Pegylated Interferon-Alpha
– Effect of Biomodulina-T® and VA-MENGOC-BC® on lymphocyte subpopulations in older adults
En la sección: COVID-19, Infectología, Inmunidad innata, Inmunoterapia, Linfocitos T. Publicado en: .
Al menos cuatro variantes genéticas del locus del factor H del complemento se asocian con un riesgo incrementado de degeneración macular relacionada con la edad, una importante causa de ceguera, según Cipriani V, Tierney A, Griffiths JR, Zuber V, Sergouniotis PI, Yates JRW, et al. Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations. Am J Hum Gen, 2021;108(8):1385-1400.
En la sección: Inmunidad innata, Inmunología en otras especialidades. Publicado en: .
– Diagnostic performance of anti-Zika virus IgM, IgAM and IgG ELISAs during co-circulation of Zika, dengue, and chikungunya viruses in Brazil and Venezuela
– Revisiting Pleiotropic Effects of Type I Interferons: Rationale for Its Prophylactic and Therapeutic Use Against SARS-CoV-2
– Effect of Age on the Immune and Visceral Organ Weights and Cecal Traits in Modern Broilers
– Differential Induction Pattern Towards Classically Activated Macrophages in Response to an Immunomodulatory Extract from Pleurotus ostreatus Mycelium
En la sección: Artículos de revisión, Autores cubanos en revistas extranjeras, COVID-19, Infectología, Inmunidad innata, Inmunología veterinaria, Inmunoterapia, Tecnologías. Publicado en: .
– Protecting the Immunosuppressed against Covid-19 (audio descargable, 26,2 MB, 22:41 minutos)
– Complement control for COVID-19
– Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection
– Core Concept: Herd immunity is an important—and often misunderstood—public health phenomenon
En la sección: Actualidades, COVID-19, Debates, Infectología, Inmunidad innata, Inmunodeficiencias. Publicado en: .