Warkentin (Aug. 13 issue) highlights the misconception that all cases of ischemic limb gangrene are associated with the loss of an arterial pulse and presents the two syndromes associated with disseminated intravascular coagulation in which ischemic limb gangrene can occur with a pulse. However, in so doing, he may have created another misconception — the idea that ischemic limb gangrene with pulses is related to syndromes associated with disseminated intravascular coagulation. It is important to recognize that ischemic limb gangrene with pulses can occur without associated disseminated intravascular coagulation, as it does in calcific uremic arteriolopathy (calciphylaxis) and cholesterol embolization (atheroembolism). Leer más…