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Therapeutic protocol using growth factors in electrocution wounds – case reports and review of the literature.

Teodoreanu, R. N. et als.
Rom J Morphol Embryol. 2014;55(2):473-82.

RMJE - Vol. 25Injuries by high voltage electrocution represent rare and very complex accidents. In order to provide support to surgical therapy, to limit the extension of injuries or to support the natural process of tissue repair, we oriented towards the use of two growth factors, insulin and platelet-enriched plasma (PRP) administered locally, on the injury site. The therapeutic protocol was applied on three cases of electrocution with promising results in reducing the duration of surgical and pharmacological treatment and of time of hospitalization. The influence of growth factors on healing wounds, the mechanism of action and recent therapeutic applications are also discussed.

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New treatment strategies to reduce burn wound progression

Schmauss, D. et als.
GMS Ger Plast Reconstr Aesthet Surg. 2014;4:Doc01.

German Plastic & Reconstructive Aesthetic Surgery - Vol. 4After a burn injury certain superficial partial-thickness burn wounds spontaneously progress into deep partial-thickness or full-thickness burn wounds. This poorly understood phenomenon is called burn wound progression. The aim of this study was to investigate whether treatment strategies using warm water (preservation of microcirculation) on the one side and erythropoietin (EPO) (molecule with anti-inflammatory, anti-apoptotic, vasodilatory and neoangiogenic properties) can prevent, delay and/or reduce secondary burn wound progression in a rat model.

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Up-to-date use of honey for burns treatment

Zbuchea, A.
Ann Burns Fire Disasters. 2014; 27(1): 22–30.

Annals Burns Fire Disasters - Vol. 27Made by bees from the nectar of flowers, used since ancient times to treat wounds and burns, honey has lately acquired a growing interest from the international scientific community and has been the subject of many specialized studies and communications. This article highlights the up-to-date knowledge on qualities, properties and mode of appliance of honey in the treatment of wounds of various etiologies, particularly burns, through an extensive retrospective analysis of data from the literature.

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Burn wound healing with injection of adipose-derived stem cells: a mouse model study

Karimi, H; Soudmand, A; Orouji, Z; Taghiabadi, E; Mousavi, S. J.
Ann Burns Fire Disasters. 2014;27(1):44-9

Stem cellAnnals Burns Fire Disasters - Vol. 27s have shown promise with regard to the healing process of burn wounds. However, donor sites for these cells are still under investigation. The aim of this study is to review the efficacy of adipose tissue-derived stem cells (ADSCs) in accelerating wound healing of third degree burns in a mouse model.

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Combined use of negative pressure wound therapy and Integra® to treat complex defects in lower extremities after burns

González A., I. et al.
Ann Burns Fire Disasters. 2013. 26(2): 90-93

Annals Burns Fire Disasters - Vol. 26Deep and extensive burns of lower extremities present a difficult challenge to healthcare professionals.In dealing with such complex wounds, which are difficult to treat, several authors have recommended the combined use of Integra® and negative pressure wound therapy (NPWT). They emphasize that NPWT eliminates wound exudate, promotes neovascularisation and cell migration through the Integra® matrix while increasing its stability and adherence to the wound bed, as well as decreasing the time needed for its total integration. The case presented here is of a patient with major third-degree flame burns to the lower extremities.

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