, M. A; , R; , A; , S.
European Journal of Plastic Surgery, April 2019, Volume 42, Issue 2, pp 177–182
Burns are a major health problem worldwide. In some countries, they are the fourth leading cause of death in trauma patients. Every year, more than 200,000 deaths occur because of diverse types of burns, and the majority of these deaths occur in low-income countries. The incidence of burn mortality depends on both patient factors (age, gender, and comorbidities) and burn factors (depth and total burn surface area (TBSA)). Mortality prediction for burn patients is important not only to determine the prognosis of individual patients but to assess the performance of the burn institute and the quality of the health care the patients receive. Many mortality or survival prediction models have been developed, modified, and validated. The abbreviated burn scoring index (ABSI) is one of the most commonly used scores for assessing patients’ mortality. It was reviewed, modified, and validated in this study.
Burns are a significant cause of trauma, and over the years, the focus of patient care has shifted from just survival to facilitation of improved functional outcomes. Typically, burn treatment, especially in the case of extensive burn injuries, involves surgical excision of injured skin and reconstruction of the burn injury with the aid of skin substitutes. Conventional skin substitutes do not contain all skin cell types and do not facilitate recapitulation of native skin physiology. Three-dimensional (3D) bioprinting for reconstruction of burn injuries involves layer-by-layer deposition of cells along with scaffolding materials over the injured areas. Skin bioprinting can be done either in situ or in vitro.
Recently, many studies have demonstrated pleotropic effects of vitamin D, including immune modulation and cardiovascular system activity. Sufficient vitamin D concentrations and supplementation of vitamin D may be of benefit in burn-injured patients. Low 25(OH)D has been observed in nearly all pediatric and most adult burn patients.
Las heridas por quemadura causan niveles altos de morbilidad y mortalidad en todo el mundo. Los pacientes con quemaduras son particularmente vulnerables a las infecciones; más del 75% de todas las muertes debido a quemaduras (después de la reanimación inicial) son resultado de la infección. Los antisépticos son agentes tópicos que actúan para prevenir el crecimiento de microorganismos. Se utiliza una amplia variedad con la intención de prevenir la infección y promover la cicatrización de las heridas por quemadura.
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