Varkey, M. et als.
Burns & Trauma. 2019; 7:4
Burns are a significant cause of trauma, and over the years, the focus of patient care has shifted from just survival to facilitation of improved functional outcomes. Typically, burn treatment, especially in the case of extensive burn injuries, involves surgical excision of injured skin and reconstruction of the burn injury with the aid of skin substitutes. Conventional skin substitutes do not contain all skin cell types and do not facilitate recapitulation of native skin physiology. Three-dimensional (3D) bioprinting for reconstruction of burn injuries involves layer-by-layer deposition of cells along with scaffolding materials over the injured areas. Skin bioprinting can be done either in situ or in vitro.

Recently, many studies have demonstrated pleotropic effects of vitamin D, including immune modulation and cardiovascular system activity. Sufficient vitamin D concentrations and supplementation of vitamin D may be of benefit in burn-injured patients. Low 25(OH)D has been observed in nearly all pediatric and most adult burn patients.
Las heridas por quemadura causan niveles altos de morbilidad y mortalidad en todo el mundo. Los pacientes con quemaduras son particularmente vulnerables a las infecciones; más del 75% de todas las muertes debido a quemaduras (después de la reanimación inicial) son resultado de la infección. Los antisépticos son agentes tópicos que actúan para prevenir el crecimiento de microorganismos. Se utiliza una amplia variedad con la intención de prevenir la infección y promover la cicatrización de las heridas por quemadura.
Polyneuropathy is a debilitating condition which may be associated with large burns. The aim of this integrative review is to identify factors that contribute to the development of critical care polyneuropathy in patients admitted to an intensive care unit with a severe burn injury. PubMed, Scopus, CINHAL and EMBASE were searched up until July 2016. Studies/case reports focusing on critical care polyneuropathy for burn injured patients were included.




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