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Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) and the textured breast implant crisis

Groth, A; Graf, R.
Aesthetic Plastic Surgery, February 2020, Volume 44, Issue 1

portada - Aesthetic Plastic Surgery - Vol. 41; No. 2 (2017)Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon T-cell, CD-30+/ALK lymphoma. Late (9 years) periprosthetic fluid (seroma) is the most common presentation (90% of the cases). A combination of textured breast implant, bacterial contamination, and genetic predisposition seems to be necessary for BIA-ALCL to occur. There are 35 million patients with implants in the world, and at the present moment, 573 cases of BIA-ALCL have been reported.

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U.S. epidemiology of breast implant-associated anaplastic large cell lymphoma

Doren, E. L. et als.
Plastic & Reconstructive Surgery – May 2017 – Volume 139 – Issue 9 – p 1042–1050

portada - PRS - Vol. 132; No. 2 (2013)Breast implant–associated anaplastic large cell lymphoma (ALCL) is a distinctive type of T-cell lymphoma that arises around breast implants. Although rare, all cases with adequate history have involved a textured breast implant. The objective of this study was to determine the U.S. incidence and lifetime prevalence of breast implant–associated ALCL in women with textured breast implants.
This study demonstrates a statistically significant association between textured breast implants and breast implant–associated ALCL. Although women with a textured breast implant have a low risk of developing breast implant–associated ALCL, the current U.S. incidence is significantly higher than that of primary ALCL of the breast in the general population.

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Breast implant–associated anaplastic large cell lymphoma: updated results from a structured expert consultation process

Benjamin, K. et als.
Plastic and Reconstructive Surgery – Global Open. 2015;3(1):e296.

PRS Global Open - Vol. 3Despite increased cases published on breast implant–associated anaplastic large cell lymphoma (BIA-ALCL), important clinical issues remain unanswered. We conducted a second structured expert consultation process to rate statements related to the diagnosis, management, and surveillance of this disease, based on their interpretation of published evidence.

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