Gus, E; Shahrokhi, S; Jeschke, M.
Burns, 2020-02-01, Volumen 46, Número 1, Páginas 19-32
Major thermal injury induces profound metabolic derangements secondary to an inflammatory “stress-induced” hormonal environment. Several pharmacological interventions have been tested in an effort to halt the hypermetabolic response to severe burns. Insulin, insulin growth factor 1, insulin growth factor binding protein 3, metformin, human growth hormone, thyroid hormones, testosterone, oxandrolone, and propranolol, among others, have been proposed to have anabolic or anticatabolic effects.
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon T-cell, CD-30+/ALK lymphoma. Late (9 years) periprosthetic fluid (seroma) is the most common presentation (90% of the cases). A combination of textured breast implant, bacterial contamination, and genetic predisposition seems to be necessary for BIA-ALCL to occur. There are 35 million patients with implants in the world, and at the present moment, 573 cases of BIA-ALCL have been reported.
Dunedin is a small city located in the southeastern part of the South Island of New Zealand, an enclave found in the Southern Hemisphere halfway around the World. How possibly would anyone consider such a remote place to be the birthplace of modern plastic surgery? Yet here was born both Sir Harold Delf Gillies, the “father of modern plastic surgery.”
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