octubre 2011 Archives

Instructivo de aplicación del producto HEBERPROT-P

El Centro de Ingeniería Genética y Biotecnológica de Cuba ha publicado este folleto que explica resumidamente la forma de aplicación de este nuevo producto que favorece la cicatrización de las úlceras del pié diabético. El folleto además posee secciones que describen la historia, resultados preclínicos, resultados clínicos, publicaciones, patentes y preguntas frecuentes.

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Dres. Veronique Bataile, Esther de Vries.
BMJ, nov 2008.
  
La incidencia de melanoma ha aumentado en los últimos 30 años en la mayoría de las personas de piel blanca.  El reconocimiento temprano del melanoma es una tarea importante para los profesionales de la salud.  En éste articulo se examina la epidemiología genética del melanoma y las interacciones complejas entre la incidencia, mortalidad y sobrevida, también se discute sobre la prevención.

 
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Obesity and the Skin
A.R. Shipman; G.W.M. Millington
Obesity is a serious global health problem, perhaps the biggest public health issue of our times. Excess body weight may be a factor in carcinogenesis in general, as well as contributing to the pathogenesis of metabolic, cardiovascular and musculoskeletal disorders. Obesity also has many cutaneous features, which form the basis for this review article. Many of these clinical entities are common to the majority of obese patients, e.g. striae distensae, plantar hyperkeratosis and an increased risk of skin infections. However, it may also be associated with poor wound healing, malignant melanoma and an increased risk of inflammatory dermatoses, such as psoriasis, as well as some rarer disorders. Therapeutic interventions for obesity, whether over-the-counter, prescription medicines or surgical interventions, are increasingly commonplace. All of these treatment modalities potentially have dermatological side-effects too.

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Management of Psoriatic Arthritis From the View of the Dermatologist CME
Caroline A. Chang, MD; Alice B. Gottlieb, MD, PhD; Paul F. Lizzul, MD, PhD, MPH, MBA

Psoriatic arthritis (PsA) is an inflammatory seronegative spondyloarthropathy associated with psoriasis. Although the main assessment measures for PsA are borrowed from the standard criteria used to assess rheumatoid arthritis, a number of new criteria such as the PsAJAI and CPDAI are being developed specifically for PsA. Long-term consequences of untreated PsA include persistent inflammation, progressive joint damage and, in many cases, substantial functional limitations, pain and disability. Moreover, patients with PsA have an increased mortality risk and an increased risk of developing cardiovascular disease and metabolic syndrome. Both GRAPPA and the AAD have developed treatment guidelines, which are discussed here. Psoriasis commonly precedes arthritic symptoms; thus, dermatologists are ideally placed to make the initial diagnosis of PsA and treat it appropriately, affording the opportunity to slow disease progression, improve physical function and enhance quality of life. This Review explores the management of patients with PsA, with a particular emphasis on assessment tools, long-term consequences and treatment issues from the viewpoint of the dermatologist.

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